{"id":1600,"date":"2022-03-24T11:34:18","date_gmt":"2022-03-24T11:34:18","guid":{"rendered":"https:\/\/linksus.net\/moderna-says-its-low-dose-covid-shots-work-for-kids-under-6-the-associated-press-en-espanol\/"},"modified":"2022-03-24T11:34:18","modified_gmt":"2022-03-24T11:34:18","slug":"moderna-says-its-low-dose-covid-shots-work-for-kids-under-6-the-associated-press-en-espanol","status":"publish","type":"post","link":"https:\/\/linksus2.linksus.net\/index.php\/2022\/03\/24\/moderna-says-its-low-dose-covid-shots-work-for-kids-under-6-the-associated-press-en-espanol\/","title":{"rendered":"Moderna says its low-dose COVID shots work for kids under 6 – The Associated Press – en Espa\u00f1ol"},"content":{"rendered":"

Moderna\u2019s COVID-19 vaccine works in babies, toddlers and preschoolers, the company announced Wednesday \u2014 a development that could pave the way for the littlest kids to be vaccinated by summer if regulators agree.
Moderna said that in the coming weeks it would ask regulators in the U.S. and Europe to authorize two small-dose shots for youngsters under 6. The company also is seeking to have larger doses cleared for older children and teens in the U.S.
The announcement is positive news for parents who have anxiously awaited protection for younger tots and been continuously disappointed by setbacks and confusion <\/a> over which shots might work and when. The nation\u2019s 18 million children under 5 are the only age group not yet eligible for vaccination.
Moderna says early study results show tots develop high levels of virus-fighting antibodies from shots containing a quarter of the dose given to adults. Once Moderna submits its full data, the U.S. Food and Drug Administration will have to determine if that important marker means the youngsters are as protected against severe illness as adults.
\u201cThe vaccine provides the same level of protection against COVID in young kids as it does in adults. We think that\u2019s good news,\u201d Dr. Stephen Hoge, Moderna\u2019s president, told The Associated Press.
But that key antibody finding isn\u2019t the whole story. COVID-19 vaccines aren\u2019t as effective against the super-contagious omicron mutant<\/a> \u2014 in people of any age \u2014 and Moderna\u2019s study found the same trend. There were no severe illnesses during the trial but the vaccine was only about 44% effective at preventing milder infections in babies up to age 2, and nearly 38% effective in the preschoolers.
\u201cNot a home run\u201d but the shots still could be helpful for the youngest children, said Dr. Jesse Goodman of Georgetown University, a former FDA vaccine chief. Goodman said the high antibody levels seen in the study \u201cshould translate into higher efficacy against severe infections.\u201d
Some parents say even a little protection would be better than leaving their youngest children unvaccinated.
\u201cI don\u2019t care if it\u2019s even 15 or 20%,\u201d said Lauren Felitti of Gaithersburg, Maryland. Her 4-year-old son Aiden, who\u2019s at extra risk because of a heart condition, was hospitalized for eight days with COVID-19 and she\u2019s anxious to vaccinate him to lessen the chance of a reinfection.
\u201cIt was very scary,\u201d Felitti said. \u201cIf there\u2019s a chance that I\u2019m able to keep him protected, even if it\u2019s a small chance, then I\u2019m all for it.\u201d
Competitor Pfizer currently offers kid-size doses for school-age children and full-strength shots for those 12 and older. And the company is testing even smaller doses for children under 5 but had to add a third shot to its study when two didn\u2019t prove strong enough. Those results are expected by early April.
If the FDA eventually authorizes vaccinations for little kids from either company, there still would be another hurdle. The Centers for Disease Control and Prevention recommends who should get them \u2014 and Goodman said there may be debate about shots for higher-risk children or everyone under 5.
Vaccinating the littlest \u201chas been somewhat of a moving target over the last couple of months,\u201d Dr. Bill Muller of Northwestern University, who is helping study Moderna\u2019s pediatric doses, said in an interview before the company released its findings. \u201cThere\u2019s still, I think, a lingering urgency to try to get that done as soon as possible.\u201d
While COVID-19 generally isn\u2019t as dangerous to youngsters as to adults, some do become severely ill. The CDC says about 400 children younger than 5 have died from COVID-19 since the pandemic\u2019s start. The omicron variant hit children especially hard, with those under 5 hospitalized at higher rates than at the peak of the previous delta surge.
The younger the child, the smaller the dose being tested. Moderna enrolled about 6,900 kids under 6 \u2014 including babies as young as 6 months \u2014 in a study of the 25-microgram doses.
While the study wasn\u2019t large enough to detect very rare side effects, Moderna said the small doses were safe and that mild fevers, like those associated with other common pediatric vaccines, were the main reaction.
Hudson Diener, 3, only briefly cried when getting test doses at Stony Brook Medicine in Commack, New York. His parents welcomed the study results and hope to learn that Hudson received the vaccine and not dummy shots.
\u201cWe are really hoping to get the answer we\u2019re looking for soon so we can take a deep breath,\u201d said Hudson\u2019s mom, Ilana Diener. Wednesday\u2019s news should \u201chopefully be a step closer for his age group to be eligible for the vaccine very soon.\u201d
Boosters have proved crucial for adults to fight omicron and Moderna currently is testing those doses for children as well \u2014 either a third shot of the original vaccine or an extra dose that combines protection against the original virus and the omicron variant.
Parents may find it confusing that Moderna is seeking to vaccinate the youngest children before it\u2019s cleared to vaccinate teens. While other countries already have allowed Moderna\u2019s shots to be used in children as young as 6, the U.S. has limited its vaccine to adults.
The FDA hasn\u2019t ruled on Moderna\u2019s earlier request to expand its shots to 12- to 17-year-olds because of concern about a very rare side effect. Heart inflammation sometimes occurs in teens and young adults, mostly males, after receiving either the Pfizer or Moderna vaccines. Moderna is getting extra scrutiny because its shots are a far higher dose than Pfizer\u2019s.
The company said Wednesday that, armed with additional evidence, it is updating its FDA application for teen shots and requesting a green light for 6- to 11-year-olds, too. Hoge said he\u2019s optimistic the company will be able to offer its vaccine \u201cacross all age groups in the United States by the summer.\u201d
Moderna says its original adult dose \u2014 two 100-microgram shots \u2014 is safe and effective in 12- to 17-year-olds. For elementary school-age kids, it\u2019s using half the adult dose.
About 1.5 million adolescents have used the Moderna vaccine in other countries, \u201cand so far we\u2019ve seen very reassuring safety from that experience,\u201d Hoge said.
The heart risk also seems linked to puberty, and regulators in Canada, Europe and elsewhere recently expanded Moderna vaccinations to kids as young as 6.
\u201cThat concern has not been seen in the younger children,\u201d said Northwestern\u2019s Muller.
___
AP video journalist Emma H. Tobin in New York City and reporter Ben Finley in Norfolk, Virginia, contributed to this report.
___
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute\u2019s Department of Science Education. The AP is solely responsible for all content.<\/p>\n

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Moderna\u2019s COVID-19 vaccine works in babies, toddlers and preschoolers, the company announced Wednesday \u2014 a development that could pave the way for the littlest kids to be vaccinated by summer if regulators agree.Moderna said that in the coming weeks it would ask regulators in the U.S. and Europe to authorize two small-dose shots for youngsters […]<\/p>\n","protected":false},"author":869,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[],"tags":[],"_links":{"self":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/posts\/1600"}],"collection":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/users\/869"}],"replies":[{"embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/comments?post=1600"}],"version-history":[{"count":0,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/posts\/1600\/revisions"}],"wp:attachment":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/media?parent=1600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/categories?post=1600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/tags?post=1600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}