{"id":1987,"date":"2022-03-25T22:38:37","date_gmt":"2022-03-25T22:38:37","guid":{"rendered":"https:\/\/linksus.net\/ivermectin-not-a-miracle-drug-in-covid-19-new-study-shows-medical-news-today\/"},"modified":"2022-03-25T22:38:37","modified_gmt":"2022-03-25T22:38:37","slug":"ivermectin-not-a-miracle-drug-in-covid-19-new-study-shows-medical-news-today","status":"publish","type":"post","link":"https:\/\/linksus2.linksus.net\/index.php\/2022\/03\/25\/ivermectin-not-a-miracle-drug-in-covid-19-new-study-shows-medical-news-today\/","title":{"rendered":"Ivermectin not a &#039;miracle drug&#039; in COVID-19, new study shows &#8211; Medical News Today"},"content":{"rendered":"<p><em>All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. Visit our <\/em><a href=\"\/coronavirus\" class=\"content-link css-1pg8eb5\">coronavirus hub<\/a> <em>and follow our <\/em><a href=\"\/articles\/live-updates-coronavirus-covid-19\" class=\"content-link css-1pg8eb5\">live updates page<\/a><em> for the most recent information on the COVID-19 pandemic.<\/em><br \/>Medical experts have spent the better part of the last 3 years developing scientific strategies to overcome SARS-CoV-2, the virus responsible for COVID-19. <br \/>Currently, some of the most important developments have been <a href=\"\/articles\/coronavirus-vaccine\" class=\"content-link css-1pg8eb5\">COVID-19 vaccines<\/a>, <hl-trusted-source source=\"Food and Drug Administration (FDA)\" rationale=\"Governmental authority\"><a href=\"https:\/\/www.fda.gov\/consumers\/consumer-updates\/know-your-treatment-options-covid-19#:~:text=The%20FDA%20has%20approved%20the,Emergency%20Use%20Authorization%20(EUA)%20.\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1pg8eb5\">COVID-19 treatments<\/a><\/hl-trusted-source>, and measures such as physical distancing and wearing a mask.<br \/>However, there have been several reports of other potential therapies capable of \u201cprotecting\u201d against COVID-19. <br \/>Of note is <a href=\"\/articles\/ivermectin-oral-tablet\" class=\"content-link css-1pg8eb5\">ivermectin<\/a>, an inexpensive and easily accessible antiparasitic drug that has quickly gained popularity worldwide. <br \/>Although several <hl-trusted-source source=\"BMC\/BioMed Central\" rationale=\"Peer reviewed journal\"><a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06348-5?fbclid=IwAR2I03VuTDVQ7WFdKprDoasgfbMNkxmJwW3zT2fVXZ4SSXQHQc7RcafX2Qc\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1pg8eb5\">studies<\/a><\/hl-trusted-source> have shown that ivermectin has no significant effect on symptoms or hospitalization rates for people with COVID-19, it is still widely prescribed. <br \/>Now, a recent study by scientists in Malaysia has set out to determine whether ivermectin has any role in treating the illness.<br \/>The study authors conclude that their findings have \u201cdismissed the notion of ivermectin being a \u2018miracle drug\u2019 against COVID-19.\u201d<br \/>The findings have been published in <em><hl-trusted-source source=\"JAMA\" rationale=\"Highly respected journal,Expert written journal,Peer reviewed journal\"><a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2789362?guestAccessKey=58760460-df0f-4790-9257-8f3682dca39b&#038;utm_source=For_The_Media&#038;utm_medium=referral&#038;utm_campaign=ftm_links&#038;utm_content=tfl&#038;utm_term=021822\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1pg8eb5\">JAMA Internal Medicine<\/a><\/hl-trusted-source>.<\/em><br \/>Lead study author <a href=\"https:\/\/www.researchgate.net\/profile\/Steven-Chee-Loon-Lim\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1pg8eb5\">Dr. Steven Chee Loon Lim<\/a>, an infectious diseases consultant at the Raja Permaisuri Bainun Hospital, in Ipoh, explained the findings to <em>Medical News Today<\/em>: <br \/><strong>\u201cOur study showed that ivermectin treatment during early COVID-19 illness did not reduce the risk of progression to severe disease.\u201d<\/strong><br \/>\u201cAmong the patients who developed severe disease during the study period, 21.6% received ivermectin plus standard of care, and 17.3% received standard of care alone,\u201d Dr. Lim explained. <br \/>\u201cThere were also no statistically significant effects in the rate of mechanical ventilation, [intensive care unit (ICU)] admission, mortality, symptom resolution, and duration of hospital stay [between both groups],\u201d he concluded. <br \/>The team conducted the study at 20 government hospitals and a COVID-19 quarantine center in Malaysia. Between May and October 2021, they enrolled 500 participants who had tested positive for COVID-19. <br \/>The researchers excluded people who were asymptomatic, pregnant, breastfeeding, or who had taken ivermectin or antiviral medicines in the 7 days before enrollment. <br \/>The study participants were 50 years or older, had at least one comorbidity, and presented with mild to moderate COVID-19 illness within 7 days of developing symptoms. <br \/>The researchers grouped the participants according to the clinical severity of the illness at presentation and the stage of disease progression. The categories included:<br \/>The team classified stages 2 and 3 as mild and moderate disease states, and stages 4 and 5 as severe. <br \/>Finally, the scientists assigned the study participants at random to either the intervention group \u2014 which received an oral dose of ivermectin plus the standard of care \u2014 or the control group, which received only the standard of care. <hl-trusted-source source=\"PubMed Central\" rationale=\"Highly respected database from the National Institutes of Health\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3136079\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1pg8eb5\">Randomization<\/a><\/hl-trusted-source> is a research technique that helps reduce the risk of accidental bias. <br \/>The results showed that 95 participants, or 19.4%, experienced severe disease over the course of the study. <br \/>Of this number, 52 had received ivermectin plus the standard of care, while 43 had received the standard of care alone: 21.6% compared with 17.3%, respectively. <br \/>The team noted that the time from enrollment to the onset of severe complications was similar for the intervention and control groups: 2.4 days versus 1.8 days. <br \/>Additionally, both groups had comparable hospital stay durations and in-hospital mortality rates. <br \/>The scientists also reported that ICU admission occurred for 6 individuals in the intervention group and 8 individuals in the control group: 2.5% versus 3.2%. <br \/>These findings led the scientists to conclude that \u201cIn high-risk patients with mild to moderate COVID-19, ivermectin treatment in early illness did not prevent progression to severe disease.\u201d<br \/>A similar conclusion was shared by <a href=\"https:\/\/www.vumc.org\/health-policy\/person\/william-schaffner-md\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1pg8eb5\">Dr. William Schaffner<\/a>, a professor of medicine at the Vanderbilt University School of Medicine, in Nashville, TN. <br \/><strong>He told <em>MNT<\/em> that \u201cThe [study] results reinforce the previously established assessment that ivermectin does not have a place in the treatment of COVID-19 infections.\u201d<\/strong><br \/>\u201cFortunately, there now are other proven, effective treatments and vaccines that are being used to combat COVID-19,\u201d Prof. Schaffner noted.<br \/>The researchers note that their study design may have contributed to underreporting of adverse effects in the control group while overestimating the effects of ivermectin.<br \/>They also explain that their study was not designed to measure the effects of ivermectin on mortality rates.<br \/>Finally, the researchers acknowledge that their findings may be limited by the older age of the study population. Nonetheless, they maintain the validity and strengths of their findings.<br \/><a class=\"css-onvglr\" data-event=\"engagement|bottom page content promo click|\/articles\/science-is-flawed-covid-19-ivermectin-and-beyond;engagement|bottom page content promo click index|1\" data-element-event=\"INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|\u2018Science is flawed\u2019: COVID-19, ivermectin, and beyond|rn0\" href=\"\/articles\/science-is-flawed-covid-19-ivermectin-and-beyond\" data-testid=\"text-link\" aria-hidden=\"true\" tabindex=\"-1\">In this op-ed, epidemiologist Gideon Meyerowitz-Katz discusses problems with medical research that have become increasingly apparent during the\u2026<\/a><br \/><a class=\"css-onvglr\" data-event=\"engagement|bottom page content promo click|\/articles\/covid-19-symptoms;engagement|bottom page content promo click index|2\" data-element-event=\"INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|What are the symptoms of COVID-19?|rn1\" href=\"\/articles\/covid-19-symptoms\" data-testid=\"text-link\" aria-hidden=\"true\" tabindex=\"-1\">The main symptoms of COVID-19 are fever, dry cough, and shortness of breath. Learn more about the other symptoms and what to expect here.<\/a><br \/><a class=\"css-onvglr\" data-event=\"engagement|bottom page content promo click|\/articles\/what-are-the-neurological-complications-of-covid-19;engagement|bottom page content promo click index|3\" data-element-event=\"INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|What are the neurological complications of COVID-19?|rn2\" href=\"\/articles\/what-are-the-neurological-complications-of-covid-19\" data-testid=\"text-link\" aria-hidden=\"true\" tabindex=\"-1\">A new study has looked into the neurological complications that COVID-19 can cause in some patients, including instances of brain inflammation.<\/a><br \/><a class=\"css-onvglr\" data-event=\"engagement|bottom page content promo click|\/articles\/long-covid-brain-fog-what-do-we-know-about-the-neurocognitive-impact;engagement|bottom page content promo click index|4\" data-element-event=\"INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|In Conversation: The neurocognitive impact of long COVID|rn3\" href=\"\/articles\/long-covid-brain-fog-what-do-we-know-about-the-neurocognitive-impact\" data-testid=\"text-link\" aria-hidden=\"true\" tabindex=\"-1\">What do we know about the long-term neurocognitive impact of COVID-19, and what are we yet to learn? This Special Feature and podcast investigate<\/a><br \/><a class=\"css-onvglr\" data-event=\"engagement|bottom page content promo click|\/articles\/why-is-covid-19-on-the-rise-in-asia-and-what-does-this-mean-for-the-us;engagement|bottom page content promo click index|5\" data-element-event=\"INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Why is COVID-19 on the rise in Asia, and what does this mean for the US?|rn4\" href=\"\/articles\/why-is-covid-19-on-the-rise-in-asia-and-what-does-this-mean-for-the-us\" data-testid=\"text-link\" aria-hidden=\"true\" tabindex=\"-1\">Hong Kong and other regions have been experiencing a surge of COVID-19 cases. Does this have any implications for the United States?<\/a><br \/>OUR BRANDS<\/p>\n<p><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/not-a-miracle-drug-experts-on-ivermectin-in-covid-19-treatment\">source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. Visit our coronavirus hub and follow our live updates page for the most recent information on the COVID-19 pandemic.Medical experts have spent the better part of the last 3 years developing scientific strategies [&hellip;]<\/p>\n","protected":false},"author":869,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[],"tags":[],"_links":{"self":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/posts\/1987"}],"collection":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/users\/869"}],"replies":[{"embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/comments?post=1987"}],"version-history":[{"count":0,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/posts\/1987\/revisions"}],"wp:attachment":[{"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/media?parent=1987"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/categories?post=1987"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/linksus2.linksus.net\/index.php\/wp-json\/wp\/v2\/tags?post=1987"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}